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<br> The intermediate filaments anchor the thin filaments and correspond to the Z-disks of skeletal muscle. During contraction, the sleek-muscle cell's intermediate filaments help to draw the cell up, like closing a drawstring purse. In smooth-muscle cells, intermediate filaments are interlaced through the cell much just like the threads in a pair of "fish-web" stockings. Calcium ions bind to troponin-tropomyosin molecules located within the grooves of the actin filaments. They transfer the troponin-tropomyosin complicated off the binding sites, allowing actin and myosin to work together. Myosin kinds crossbridges with actin (as happens in skeletal muscle). Cardiac-muscle contraction is actin-regulated, meaning that the calcium ions come each from the sarcoplasmic reticulum (as in skeletal muscle) and from outdoors the cell (as in clean muscle). After the action potential has handed, the calcium gates close, and calcium pumps positioned on the sarcoplasmic reticulum take away calcium from the cytoplasm. Unlike skeletal-muscle cells, smooth-muscle cells don't have any troponin, tropomyosin or organized sarcoplasmic reticulum. As the calcium gets pumped again into the sarcoplasmic reticulum, calcium ions come off the troponin. Lift the leg as excessive as attainable with out bending your knee or arching your back.<br>
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